The general arrangement of this manuscript corresponds fairly closely with that found in the printed editions, but the manuscript contains several recipes which do not appear in them, and vice versa; there are also differences in the details of recipes. The manuscript contains some additional material at the end.

The contents are as follows.

Tippermalloch's Recipes (pages 1-181);

The following note by the writer of the manuscript: 'The End Of the Famous TIPERMALLOCHS receipts ist given to --- by sr Ja: Stuart Advocat at Rotterdam [i.e., Sir James Steuart (1635-1715), Lord Advocate] Ao. 1684. From ye wch MSS. in oct. I took ys transcript wch I got from George Millar Nottar son to Gurlebank about ye Latter end of janr. 1710.' (page 181);

Further recipes in the same hand (pages 182-188);

Further recipes in a later hand (pages 188-217);

A biographical note in pencil about Sir James Steuart (page 265);

Further recipes, not medical, in a hand similar to that used in the first section of the manuscript (pages 267-269).